Study News & Selected Publications
Recent News
Recently the MINDDS II study was announced at the ANESTHESIOLOGY 2024 Annual Meeting from the American Society of Anesthesiologists in October 2024. This presentation was part of a panel on ‘NIH-Funded Clinical Trials in Anesthesiology: Current Studies, Networks and Innovations.”
During this panel, Dr. Susana Vacas, one of the MINDDS II Co-Investigators from Massachusetts General Hospital provided an update on the study, emphasizing the teamwork and communication that has made MINDDS II a success to date.
“This study and its people are a collection of intellectual talent which will lead us to a real tangible solution that clinicians will be able to offer their patients.”
Selected Publications
eClinicalMedicine
Nighttime dexmedetomidine for delirium prevention in non-mechanically ventilated patients after cardiac surgery (MINDDS): A single-centre, parallel-arm, randomised, placebo-controlled superiority trial
Association Between Postoperative Delirium and Long-Term Subjective Cognitive Decline in Older Patients Undergoing Cardiac Surgery: A Secondary Analysis of the Minimizing Intensive Care Unit Neurological Dysfunction with Dexmedetomidine-Induced Sleep Trial
Journal of Cardiothoracic and Vascular Anesthesia
British Journal of Anaesthesia
Tau as a serum biomarker of delirium after major cardiac surgery: a single centre case-control study
Frontiers in Aging Neuroscience
Serum Proteomics of Older Patients Undergoing Major Cardiac Surgery: Identification of Biomarkers Associated With Postoperative Delirium
Brain Communications
Cognitive function mediates the relationship between age and anaesthesia-induced oscillatory-specific alpha power
Journal of Cardiothoracic and Vascular Anesthesia
Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery
Anesthesiology
Sex Differences in the Incidence of Postoperative Delirium after Cardiac Surgery: A Pooled Analyses of Clinical Trials
